NANODRUG : Model For The Treatment Of Cancer?Lets Find Out!

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The project aims at encouraging nano drug therapy as an alternative treatment for cancer. Why nano drug therapy? Because this is the only treatment that doesn?t affect the healthy cells of the patient?s body and only concentrates its working on the cancer affected cells. In this way it safeguards the healthy cells of the body and doesn?t lead to the decline of health of the patient. We see no hair fall or dehydration in the individual subjected to nano therapy, unlike chemo and radiation therapy that highly affect the patient?s health.


Although the ?war on cancer? is now in its fourth decade and despite much progress has been made in categorizing the environmental causes and cellular and molecular biological basis for this dreaded disease, we still do not have a precise understanding of the differences between a cancer cell and its normal counterpart. If we do not understand cancer, we cannot control, conquer, and eliminate it. The completion of the human genome sequence and its subsequent improvements in the sequence data are important steps to fully comprehend cancer cell biology.

Nanotechnology, a new, novel focus of research evolved from the convergence and coalescence of many diverse scientific disciplines and as a general term for the creation, manipulation, and application of structures in the nanometer size range. In this article, Nano medicine aspects of nanotechnology will be stressed and will cover areas such as drug delivery systems and new drug therapies as they relate to cancer. One of the ultimate goals of Nano medicine is to create medically useful Nano devices that can function inside the body. It is envisioned that Nano devices will be hybrids of biologic molecules and synthetic polymers that can enter cells and the organelles to interact directly with DNA and proteins. Additionally, Nano medicine will have an impact on the key challenges in cancer therapy: localized drug delivery and specific targeting. Among the newly developed Nano medicine and Nano devices such as quantum dots, nanowires, nanotubes, Nano cantilevers, and Nano pores, Nano shells and nanoparticles are the most promising applications for various cancer treatments.

Nanoscale devices are 100 to 10,000 times smaller than human cells but are similar in size to large biomolecules such as enzymes and receptors. Nanoscale devices smaller than 50 nm can easily enter most cells, and those smaller than 20 nm can move out of blood vessels as they circulate through the body. Nanodevices are suitable to serve as customized, targeted drug delivery vehicles to carry large doses of chemotherapeutic agents or therapeutic genes into malignant cells while sparing healthy cells. Nanodevices can be constructed by the molding or etching, top-down approach, or by assembling structures atom by atom or molecule by molecule, bottom-up approach.

We are now closer to being able to fully characterize the differences between the normal and the tumor cell. Coupled with the use of micro dissection techniques, it is also possible to interrogate the genetic make-up of individual cell types. The hope is that use of such technologies will accelerate the progress in identifying the differences between normal and tumor cells, which in turn will lead to development of new therapies that will specifically target the cancer. The ultimate goal of these strategies is to eliminate the tumor with limited effect on normal tissue.


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